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Copovidone (PVP VA64) Technical Data Sheet - Industry Grade

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Chemical Name: Vinylpyrrolidone/vinyl acetate copolymer (PVP/VA)
Name: Copovidone (PVP VA64)
CAS NO. : 25086-89-9
Molecular formula: (C6H9NO)n(C4H6NO2)m
Availability:

Product Description:


VA64 is a copolymer of vinyl pyrrolidone and vinyl acetate. It is a white to milky white powder that easily absorbs moisture and is easily soluble in organic solvents such as water and ethanol.


  • Structure formula:

  • Appearance: White or yellowish-white powder

  • Application:

    Binder for oral  preparation by wet granulation, dry granulation and direct compression;

    Film-forming for film coating;

    Solubilizer for solid dispersion.



Product specifications:


Name

PVP VA64

PH value

3.0-7.0

K value

27-35

Monomers ( VP+VA) (%)

0.1

Water (%)

≤5.0

Sulfate ash(%)

≤0.1

Heavy metal (lead)     ppm

≤10

VA content (%)

35.3-42 max.

The product specifications for PVP VA64, also known as Polyvinylpyrrolidone VA64, are detailed as follows: The pH value of the product ranges from 3.0 to 7.0. The K value is situated between 27 and 35. The content of monomers, which includes both VP and VA, is 0.1%. The water content is controlled to be less than or equal to 5.0%. The sulfated ash content must be less than or equal to 0.1%. The concentration of heavy metals, specifically lead, is restricted to a maximum of 10 parts per million (ppm). The VA content is within the range of 35.3% to 42%, with the maximum allowed being 35.3 to 42%. All products are compliant with the Ph. Eur, USP/NF, JP, and BP certificate of analysis.


Product Performance:

  • Superior Quality and Purity: Our PVP VA64 powder, known for its 99% purity, ensures high efficacy and reliability in a wide range of applications. This pure white powder is perfect for those looking for premium organic intermediates to significantly enhance their projects, particularly when used as a fixing gel with PVP VA64 for superior bonding properties.


  • Eco-Friendly: Made from organic materials, our PVP VA64 copolymer powder is an environmentally responsible choice for clients dedicated to sustainable practices. It's ideal for those striving to reduce their carbon footprint with an eco-conscious product, aligning with the growing demand for greener alternatives in the industry.


  • Versatile Applications: The PVP VA64 copolymer powder serves as a versatile additive applicable across various industries. Its adaptability ensures it can be seamlessly integrated into numerous processes, from pharmaceuticals to cosmetics, making it a must-have for both professionals and hobbyists seeking high-performance results.


  • Trusted Brand: Our brand is synonymous with quality and excellence, providing customers with confidence in the reliability of our products. Users can trust us to supply high-quality PVP VA64 powder that consistently meets or exceeds expectations and requirements, offering a dependable solution for their needs.


  • Exceptional Performance: The copolymer structure of our product, derived from poly (1-vinylpyrrolidone-co-vinyl acetate) with CAS 50-01-1, guarantees optimal performance in any application. Notably, the solubility of PVP VA64 in PEG 400 enhances its utility in formulations, and the precise proportion of vinylpyrrolidone and vinylacetate contributes to its exceptional characteristics.
    Customers can expect remarkable outcomes and enhanced efficiency when incorporating PVP VA64 powder into their products.



Frequently Asked Questions:

1. What is Copovidone (PVP VA64)?


Copovidone (PVP VA64) is a copolymer of vinylpyrrolidone and vinyl acetate, appearing as a white or yellowish-white powder. It is well known for its excellent film-forming properties, adhesive capabilities, and solubility in water, ethanol, and other common organic solvents.


2. What are the main applications of PVP VA64?


Pharmaceutical: Used as a binder for wet granulation, dry granulation, and direct compression in oral preparations, film-forming for tablet coating, and as a solubilizer for solid dispersions.

Industrial: Used as a rewetting adhesive, paper adhesive, coating adhesive, thickener, and protective colloid in various inks.

Agriculture: Acts as an emulsifier and protective colloid in plant protection formulations.


3. Is PVP VA64 soluble in water and other solvents?


Yes, PVP VA64 is easily soluble in water, ethanol, and other common organic solvents, ensuring broad applicability in various formulations.


4. What is the appearance of PVP VA64?


It is a white to milky white powder that is highly pure and easy to handle in manufacturing environments.





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